Adaptive Deep Brain Stimulation

The brain leads. Therapy adapts.

For millions living with Parkinson’s, every day is a negotiation between symptoms and side effects. Newronika’s αDBS listens to the brain and responds in real time, so patients can simply live.

CE ✓ Marked & clinically validated across Europe
Parkinson's Treatment
86%
Patient preference for αDBS over conventional DBS
92%
Waking hours with good symptom relief
2.4×
Longer continuous symptom relief vs. leading competitor
Living with Parkinson's

What if your treatment kept up with you?

Conventional DBS delivers a fixed, unchanging signal regardless of how you feel hour to hour, whether you’ve taken medication, or how active you are. The brain changes constantly. Until now, therapy couldn’t.

Newronika’s αDBS monitors brain signals minute by minute and adjusts stimulation automatically — keeping patients in their therapeutic window, reducing side effects, and restoring the quality of life that Parkinson’s takes away.

Conventional DBS
Newronika αDBS
✗ Fixed, unchanging signal
✓ Adapts in real time
✗ Cannot sense brain state
✓ Continuous brain signal monitoring
✗ Higher side effect risk
✓ Reduced side effects
✗ Manual clinician adjustments
✓ Cloud-based intelligence
Parkinson's Treatment

Living with Parkinson's

What if your treatment kept up with you?

Conventional DBS delivers a fixed, unchanging signal regardless of how you feel hour to hour, whether you’ve taken medication, or how active you are. The brain changes constantly. Until now, therapy couldn’t.

Newronika’s αDBS is designed to monitor brain signals minute by minute and adjust stimulation automatically — keeping patients in their therapeutic window, reducing side effects, and restoring the quality of life that Parkinson’s takes away.

Neuromodulation Adaptive Deep Brain Stimulation

Our Technology

Built for the full spectrum of care.

Every component of αDBS is designed to work together — from sensing hardware to cloud intelligence.

Adaptive Closed-Loop Stimulation

responds to each patient’s unique brain signals minute-by-minute, through continuous sensing, analysis, and therapeutic adjustments.

Patented Proportional Control Algorithm

designed to linearly track neural biomarkers for precise, reliable symptom control with fewer side-effects.

Full-Spectrum Brain Sensing every 10 minutes

captures complete α/β spectrum data, building a longitudinal neural record that deepens therapy insight over time.

WebBioBank™ Cloud-Based Neural Data Platform

stores and analyzes brain activity across all implants, leveraging breakthrough AI to power therapy optimization and future biomarker discovery.

Remote Patient Monitoring

for automatic at-home data collection and transmission, allowing clinicians to assess and manage patients while allowing fewer office visits.

Designed for real-world clinical workflows

with an intuitive, streamlined programming interface intended to reduce the time and complexities of configuring adaptive & conventional DBS.

How It Works

An intelligent system that learns with every moment of therapy.

αDBS is an adaptive DBS platform that senses, analyzes, adapts, and learns from brain signals continuously. Newronika combines a patented proportional control algorithm with cloud-based data intelligence — creating therapy that becomes more precise over time.

01

Sense

Full-spectrum brain signal sensing every 10 minutes, with asymmetric sensing during stimulation.
02

Analyze

Cloud-based data intelligence processes incoming signals, building a real-time picture of brain state.
03

Adapt

Patented proportional control algorithm designed to adjust stimulation parameters automatically to maintain the therapeutic window.
04

Learn

WebBioBank™ stores longitudinal data, enabling the system to continuously refine and improve therapy over time.

Clinical Results

Tested blind.
The results speak for themselves.

Double-blind randomized crossover study

Results from our first-of-its-kind clinical trial* — a randomized, double-blind crossover study comparing adaptive DBS directly against conventional DBS as an active comparator. Pilot study, N=19, Parkinson’s Disease.
*Results pending publication

86%
Patient preference for αDBS over conventional DBS
Head-to-head vs. cDBS
+23%
Waking hours with good symptom relief versus conventional DBS average
vs. cDBS average
100%
Patient preference for aDBS for replacement patients
Patients with previous cdbs ImplantS
Join Our Journey

Setting the new standard of care together.

Partner with Newronika to bring the next generation of adaptive brain therapy to patients who need it most.

Contact Us

Let’s talk.

Whether you’re a clinician, researcher, investor, or partner — we’d love to hear from you.

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